• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

ERRα antagonist-1

CAS No. 1072145-33-5

ERRα antagonist-1 ( ERR+/- antagonist-1; ERRa antagonist-1 )

产品货号. M26207 CAS No. 1072145-33-5

ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥551 有现货
10MG ¥988 有现货
25MG ¥2001 有现货
50MG ¥3013 有现货
100MG ¥4447 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ERRα antagonist-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.
  • 产品描述
    ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively.
  • 同义词
    ERR+/- antagonist-1; ERRa antagonist-1
  • 通路
    Endocrinology/Hormones
  • 靶点
    Estrogen Receptor/ERR
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1072145-33-5
  • 分子量
    377.5
  • 分子式
    C21H19N3S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C1CN=C(S1)N1CCS\C1=N/C1c2ccccc2C=Cc2ccccc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Shi S, Liu Y, Wu J, Li Z, Zhao Y, Zhong D, Zeng F. Comparative bioavailability and tolerability of a single 20-mg dose of two fluoxetine hydrochloride dispersible tablet formulations in fasting, healthy Chinese male volunteers:an open-label, randomized-sequence, two-period crossover study. Clin Ther. 2010 Oct;32(11):1977-86.
产品手册
关联产品
  • Ulipristal acetate

    Ulipristal acetate(CDB2914) is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.

  • Norethindrone

    Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.

  • GDC-0927 racemate

    GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.