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ERRα antagonist-1
CAS No. 1072145-33-5
ERRα antagonist-1 ( ERR+/- antagonist-1; ERRa antagonist-1 )
产品货号. M26207 CAS No. 1072145-33-5
ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥551 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
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| 25MG | ￥2001 | 有现货 |
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| 50MG | ￥3013 | 有现货 |
|
| 100MG | ￥4447 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ERRα antagonist-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist.
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产品描述ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively.
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同义词ERR+/- antagonist-1; ERRa antagonist-1
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1072145-33-5
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分子量377.5
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分子式C21H19N3S2
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纯度>98% (HPLC)
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溶解度——
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SMILESC1CN=C(S1)N1CCS\C1=N/C1c2ccccc2C=Cc2ccccc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Bazedoxifene
Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively.
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Fluticasone propiona...
Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.
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Isopsoralenoside
Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects.Psoralen (P), isopsoralen (IP), psoralenoside (PO) and Isopsoralenoside (IPO) are the major coumarins and coumarin-related benzofuran glycosides in Psoraleae Fructus, which have been reported to show estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.
